Compile Data Set for Download or QSAR
Found 143 of ic50 data for polymerid = 2242
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046227(2-Amino-6-thiophen-2-ylmethyl-3,7-dihydro-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046231(2-Amino-6-furan-2-ylmethyl-3,7-dihydro-pyrrolo[3,2...)copy SMILEScopy InChI
Affinity DataIC50: 0.0570nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50195587(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046249(2-Amino-6-thiophen-3-ylmethyl-3,7-dihydro-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 0.0670nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046252(2-Amino-6-benzyl-3,7-dihydro-pyrrolo[3,2-d]pyrimid...)copy SMILEScopy InChI
Affinity DataIC50: 0.0850nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046224(2-Amino-8-[(thiophen-3-ylmethyl)-amino]-1,9-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 0.0850nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046246(2-Amino-8-[(thiophen-2-ylmethyl)-amino]-1,9-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046241(2-Amino-8-[(furan-2-ylmethyl)-amino]-1,9-dihydro-p...)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046251(2-Amino-8-benzylamino-1,9-dihydro-purin-6-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 0.470nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046221(2-Amino-6-[(thiophen-3-ylmethyl)-amino]-3,7-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 0.630nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046216(2-Amino-6-[(furan-2-ylmethyl)-amino]-3,7-dihydro-p...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046223(2-Amino-6-benzylamino-3,7-dihydro-pyrrolo[3,2-d]py...)copy SMILEScopy InChI
Affinity DataIC50: 0.850nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50608145(CHEMBL5282677)
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50608149(CHEMBL5273669)
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046243(2-Amino-6-[(thiophen-2-ylmethyl)-amino]-3,7-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50608147(CHEMBL5280395)
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50195589(2-amino-1,5-dihydro-7-[[(2S,4R)-2-(hydroxymethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K11PubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50195587(1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50195593(2-amino-1,5-dihydro-7-[[(2S)-2-(hydroxymethyl)-1-p...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K11PubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046248(2-Amino-8-[(3-methyl-thiophen-2-ylmethyl)-amino]-1...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046218(2-Amino-6-[(3-methyl-thiophen-2-ylmethyl)-amino]-3...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50608148(CHEMBL5290077)
Affinity DataIC50: 4.60nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50195597(2-amino-1,5-dihydro-7-[[N,N-bis-[2-(hydroxy)ethyl]...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K11PubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50078452((S)-3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]...)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308521(9-[6',6'-Difluoro-6'-(diethylphosphono)hexyl]-9-de...)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human erythrocyte PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorgan...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MG0PubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50214708(6-(2-amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human PNP in presence of 1 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29P31CSPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50382672(CHEMBL2024005)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant PNP using MSEG as substrate preincubated with inhibitor within 10 to 20 mins measured after 5 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0HJ2PubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046254(2-Amino-8-thiophen-3-ylmethyl-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50039549(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046236(2-Amino-8-thiophen-2-ylmethyl-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50608146(CHEMBL5281180)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50042799(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046230(2-Amino-8-furan-2-ylmethyl-1,9-dihydro-purin-6-one...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50042804(2-Amino-7-(3-chloro-benzyl)-3,5-dihydro-pyrrolo[3,...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50195591(2-amino-1,5-dihydro-7-[[[2-(hydroxy)ethyl]amino]me...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human PNP activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9K11PubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50214705(5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-1,1-di...)copy SMILEScopy InChI
Affinity DataIC50: 20.2nMAssay Description:Inhibition of human PNP in presence of 1 mM phosphateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50214705(5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-1,1-di...)copy SMILEScopy InChI
Affinity DataIC50: 20.2nMAssay Description:Inhibition of human erythrocyte PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorgan...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50214707(9-(5',5'-Difluoro-5'-phosphonopentyl)-9-deazaguani...)copy SMILEScopy InChI
Affinity DataIC50: 20.4nMAssay Description:Inhibition of human PNP in presence of 1 mM phosphateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50214707(9-(5',5'-Difluoro-5'-phosphonopentyl)-9-deazaguani...)copy SMILEScopy InChI
Affinity DataIC50: 20.4nMAssay Description:Inhibition of human erythrocyte PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorgan...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308522(9-[7',7'-Difluoro-7'-(diethylphosphono)heptyl]-9-d...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human erythrocyte PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorgan...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N58MG0PubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046255(2-Amino-8-(pyridin-3-ylamino)-1,9-dihydro-purin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50078454(2-Amino-7-pyridin-2-ylmethyl-3,5-dihydro-pyrrolo[3...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human purine nucleoside phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571C49PubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50042803(3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50042807(2-Amino-7-[1-(3-chloro-phenyl)-3-hydroxy-propyl]-3...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50046217(2-Amino-8-benzyl-1,9-dihydro-purin-6-one | CHEMBL1...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Purine nucleoside phosphorylase was evaluated against the enzyme from Human erythrocytic in 50 mM phosphateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27TCXPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50078452((S)-3-(2-Amino-4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 50 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50042363(CHEMBL333946 | {2-[2-(2-Amino-6-oxo-1,6-dihydro-pu...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50081803(CHEMBL94840 | {1,1-Difluoro-2-[(3R,4R)-4-(6-oxo-1,...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in Cellulomonas spMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ107BPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50081806(CHEMBL94920 | {1,1-Difluoro-2-[(3R,4S)-4-(6-oxo-1,...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Compound was evaluated for inhibition of PNP-catalyzed inosine phosphorylation in Cellulomonas spMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ107BPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
BioCryst Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50042800(2-Amino-7-cyclohexylmethyl-3,5-dihydro-pyrrolo[3,2...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of Purine nucleoside Phosphorylase from calf spleen at 1 mM PO4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3DKSPubMed
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